Junction-forming aquaporins.
نویسندگان
چکیده
Aquaporins (AQPs) are a family of ubiquitous membrane channels that conduct water and solutes across membranes. This review focuses on AQP0 and AQP4, which in addition to forming water channels also appear to play a role in cell adhesion. We discuss the recently determined structures of the membrane junctions mediated by these two AQPs, the mechanisms that regulate junction formation, and evidence that supports a role for AQP0 and AQP4 in cell adhesion.
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ورودعنوان ژورنال:
- Current opinion in structural biology
دوره 18 2 شماره
صفحات -
تاریخ انتشار 2008